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Does Accutane cause back pain? Joint and muscle problems Tell your doctor if you plan to do hard physical activity during treatment with isotretinoin. Isotretinoin can cause pain in your bones, joints, muscles, and ligaments. new back pain. new joint pain. Can isotretinoin kill you? A New Jersey man won a $25 million verdict after he alleged that Roche (RHHBY.PK)'s acne drug Accutane gave him an inflamatory bowel disorder that required the removal of his colon. Taking Accutane can kill you. Or, if you get pregnant, it can kill your baby. Do doctors still prescribe Accutane? Acne Drug Accutane No Longer Sold. Generic versions of the acne drug, called isotretinoin, are still available from several manufacturers. But Roche, which has sold the drug to 13 million patients since 1982, will not be one of them.
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