Can you take Reglan after you eat? Metoclopramide is usually taken 30 minutes before meals and at bedtime, or only with meals that usually cause heartburn. Follow your doctor's dosing instructions very carefully. How do I stop nausea from methotrexate? For very severe stomach queasiness, your doctor can prescribe an anti- nausea drug such as ondansetron (Zofran), says pharmacist James Bennett of Children's Hospital in Boston. Swap your pills. When nothing else helps, switching from oral methotrexate to the injectable version can eliminate GI distress. How long can you stay on Reglan? Reglan should be taken for only 4 to 12 weeks. NEVER USE REGLAN IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long -term use of metoclopramide can cause a serious movement disorder that may not be reversible.
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